- Uveitis as an important ocular sign to help early diagnosis in Kawasaki disease
-
Han Seul Choi, Seul Bee Lee, Jung Hyun Kwon, Hae Soon Kim, Sejung Sohn, Young Mi Hong
-
Clin Exp Pediatr. 2015;58(10):374-379. Published online October 21, 2015
-
|
Purpose Incomplete Kawasaki disease (KD) is frequently associated with delayed diagnosis and treatment. Delayed diagnosis leads to increasing risk of coronary artery aneurysm. Anterior uveitis is an important ocular sign of KD. The purpose of this study was to assess differences in laboratory findings, including echocardiographic measurements, clinical characteristics such as fever duration and treatment responses between KD patients with and... |
-
-
- An inhibitory effect of tumor necrosis factor-alpha antagonist to gene expression in monocrotaline-induced pulmonary hypertensive rats model
-
Jung Hyun Kwon, Kwan Chang Kim, Min-Sun Cho, Hae Soon Kim, Sejung Sohn, Young Mi Hong
-
Clin Exp Pediatr. 2013;56(3):116-124. Published online March 18, 2013
-
|
Purpose Tumor necrosis factor (TNF)-α is thought to contribute to pulmonary hypertension. We aimed to investigate the effect of infliximab (TNF-α antagonist) treatment on pathologic findings and gene expression in a monocrotaline-induced pulmonary hypertension rat model. MethodsSix-week-old male Sprague-Dawley rats were allocated to 3 groups: control (C), single subcutaneous injection of normal saline (0.1 mL/kg); monocrotaline (M), single subcutaneous injection of monocrotaline... |
-
-
- Mycoplasma pneumoniae infection in patients with Kawasaki disease
-
Mi Na Lee, Jie Hae Cha, Hye Mi Ahn, Jeong Hyun Yoo, Hae Soon Kim, Sejung Sohn, Young Mi Hong
-
Clin Exp Pediatr. 2011;54(3):123-127. Published online March 31, 2011
-
|
Purpose Kawasaki disease (KD) is the main cause of acquired heart disease in children. In addition to cardiovascular involvement, many complications have been recognized in KD. However, respiratory complications have been rarely reported. We investigated the differences in clinical characteristics, laboratory findings, radiography findings, and echocardiography findings of Mycoplasma pneumoniae infection and other types of pneumonia in KD patients. MethodsAmong 358 patients... |
-
-
- Serum interleukin-6, tumor necrosis factor-α and adiponectin levels in Kawasaki disease
-
Jung Ahn, Han Gyu Kim, Sejung Sohn, Young Mi Hong
-
Clin Exp Pediatr. 2010;53(1):41-47. Published online January 15, 2010
-
|
Purpose : Adiponectin is an endogenous modulator of vascular remodeling that suppresses vascular inflammation. However, the role of adiponectin in Kawasaki disease (KD) has not been elucidated. The purpose of this study is to investigate the correlation between serum adiponectin level and several parameters, such as interleukin (IL)-6, tumor necrosis factor (TNF)-α, lipid profile, and C reactive protein (CRP), and... |
-
-
- Low T3 syndrome in Kawasaki disease: Relation to serum levels of tumor necrosis factor-α, interleukin-6 and NT-proBNP
-
Hye Kyung Cho, Jin A Sohn, Hae Soon Kim, Sejung Sohn
-
Clin Exp Pediatr. 2009;52(2):234-241. Published online February 15, 2009
-
|
Purpose : We investigated the relationship between thyroid hormone and serum tumor necrosis factor (TNF-α), interleukin (IL-6) and N-terminal fragment of pro-brain natriuretic peptide (NT-proBNP) in patients with Kawasaki disease (KD).
Methods : Serum levels of thyroid hormone, TNF-α, IL-6, and NT-proBNP were measured in 52 KD patients in the acute and subacute phase and 10 patients with acute... |
-
-
- Case Report
- Kawasaki disease presenting as retropharyngeal abscess
-
Sung Yoon Cho, Hye Kyung Cho, Ky Young Cho, Hae Soon Kim, Sejung Sohn
-
Clin Exp Pediatr. 2008;51(9):1023-1027. Published online September 15, 2008
-
|
A group of patients with Kawasaki disease (KD) initially present with cervical lymphadenitis or deep neck infection. These unusual KD presentations lead to unnecessary antibiotic therapy or surgical intervention, thereby delaying intravenous immunoglobulin treatment and increasing the risk of coronary artery damage. We present four KD patients whose initial presentations mimicked a retropharyngeal abscess. Nonsuppurative cervical lymphadenitis or suspected neck... |
-
-
- Original Article
- Bacterial meningitis in children experienced at a university hospital, 1993-2006
-
Sung Yoon Cho, Tae Yeon Kim, Hyunju Lee, Kyung Hyo Kim, Eun Sun Yoo, Hae Soon Kim, Eun Ae Park, Kyung Ha Ryu, Jeong Wan Seo, Sejung Sohn, Seung Joo Lee
-
Clin Exp Pediatr. 2008;51(10):1077-1084. Published online October 15, 2008
-
|
Purpose : Despite the seriousness of bacterial meningitis in children, there is little information on the incidence, causative organisms, mortality rate and age distribution. We studied the frequency by age group and causal pathogens, and clinical characteristics in children with bacterial meningitis in the private sector in Korea.
Methods : The medical records containing the data on bacterial meningitis patients... |
-
-
- Case Report
- Bronchial foreign body aspiration diagnosed with MDCT
-
Hye Kyung Cho, Ky Young Cho, Sung Yoon Cho, Sejung Sohn
-
Clin Exp Pediatr. 2007;50(8):781-784. Published online August 15, 2007
-
|
Foreign body aspiration (FBA) is a common accident in young children. Undiagnosed and retained foreign bodies may result in severe early and late complications such as asphyxia, pneumonia, atelectasis and bronchiectasis. Moreover, because it can mimic bronchiolitis, croup or asthma, an accurate history and a high index of suspicion are of paramount importance for early diagnosis. With our experience on... |
-
-
- Original Article
- Clinical fetures of kawasaki disease in school-aged children
-
Eun Young Park, Ji Hye Kim, Hae Soon Kim, Sejung Sohn
-
Clin Exp Pediatr. 2007;50(3):292-297. Published online March 15, 2007
-
|
Purpose : Kawasaki disease (KD) rarely occurs in school-aged children. We clarified the characteristics of KD in this age group to provide tips for a high index of suspicion.
Methods : Features of 38 patients with KD who were 7 years of age or older were retrospectively reviewed.
Results : The incidence of the KD patients ≥7 years was 4.9 percent. The... |
-
-
- Case Report
- Infliximab treatment for a patient with refractory Kawasaki disease
-
Hyo-Jung Yu, Soo-Jin Lee, Sejung Sohn
-
Clin Exp Pediatr. 2006;49(9):987-990. Published online September 15, 2006
-
|
Intravenous immunoglobulin (IVIG) infusion is an effective therapy for acute Kawasaki disease (KD). Nonetheless, approximately 10 percent to 20 percent of patients have persistent or recrudescent fever despite IVIG treatment, leading to a higher risk for coronary artery aneurysms (CAA). This unresponsiveness may pose a challenge to the clinicians. Tumor necrosis factor-α levels are elevated in the acute phase of... |
-
-
- Original Article
- NT-pro BNP : A new diagnostic screening tool for Kawasaki disease
-
Hyunju Lee, Heejung Kim, Hae Soon Kim, Sejung Sohn
-
Clin Exp Pediatr. 2006;49(5):539-544. Published online May 15, 2006
-
|
Purpose : The purpose of this study was to determine whether N-terminal fragment of B-type natriuretic peptide(NT-proBNP) may be used to differentiate acute Kawasaki disease(KD) from other clinically similar diseases.
Methods : Using electrochemiluminescence immunoassay, NT-proBNP concentrations were measured in the acute phase within 10 days after the onset of KD(n=58) and in the convalescent phase, 60 to 81 days after... |
-
-
- Clinical Characteristics of Recurrent Kawasaki Disease
-
Hyun Ji Lee, Ae Ra Cho, Hae Soon Kim, Sejung Sohn
-
Clin Exp Pediatr. 2004;47(8):879-883. Published online August 15, 2004
-
|
Purpose : The purpose of this study is to investigate the clinical manifestations and the risk factors of recurrent Kawasaki disease(KD).
Methods : From March 1995 to June 2003, 14 children with recurrent KD in Ewha Womans University Hospital were retrospectively evaluated by reviewing their admission reports. The clinical characteristics, laboratory findings, treatment and complications of the recurrent KD group were... |
-
-
- Methylenetetrahydrofolate Reductase(MTHFR) Gene Expression in Kawasaki Disease
-
Hye Ryung Choi, Ae Ra Joo, Hae Soon Kim, Sejung Sohn, Young Mi Hong
-
Clin Exp Pediatr. 2004;47(7):774-778. Published online July 15, 2004
-
|
Purpose : Hyperhomocysteinemia is known as an independent risk factor for cardiovascular diseases such as atherosclesosis and myocardiac infarct. A common mutation in 5, 10-methylenetetrahydrofolate reductase(MTHFR) gene results in a valine for alanine substitution, which makes enzyme thermolabile and reduces enzymal activity. We examined the relation of MTHFR genetic mutation and Kawasaki disease.
Methods : We extracted DNA from the peripheral... |
-
-
- Clinical Characteristics of Kawasaki Disease in Infants Younger than 3 Months of Age
-
Soo Jeong Lee, So Jung Kim, Hae Soon Kim, Sejung Sohn
-
Clin Exp Pediatr. 2003;46(6):591-596. Published online June 15, 2003
-
|
Purpose : Kawasaki disease(KD) is rare in infants <3 months of age. In this younger group, the diagnosis may be delayed due to lack of most of the clinical criteria, resulting in a high risk of cardiac complications. We examined clinical characteristics in these patients for early recognition and treatment.
Methods : We conducted a retrospective study on the infants... |
-
-
- Case Report
- A Case of Kawasaki Disease Associated with Acute Renal Failure and Necrotizing Myositis
-
So Hyun Ahn, So Yun Shim, Sejung Sohn, Seung Joo Lee, Un Seop Han
-
Clin Exp Pediatr. 2003;46(2):207-209. Published online February 15, 2003
-
|
Kawasaki disease is an acute febrile vasculitis affecting primarily infants and young children. In addition to the cardiovascular involvement, it may cause inflammatory changes in various organs and body systems : digestive, respiratory, urinary, nervous and musculoskeletal. A case is reported of atypical Kawasaki disease associated with acute renal failure and necrotizing myositis in the right gastrocnemius in a 10-year-old... |
-
-
- Original Article
- Safety and Efficacy of Early Treatment with Intravenous
Immunoglobulin in Patients with Kawasaki Disease
-
Hyun Jin Kim, Hae Won Yom, Hae Soon Kim, Sejung Sohn
-
Clin Exp Pediatr. 2003;46(10):1019-1023. Published online October 15, 2003
-
|
Purpose : To determine the differences in clinical characteristics, blood chemistry and coronary artery complications between patients with Kawasaki disease who received intravenous immunoglobulin (IVIG) within the fourth day of illness and after the fifth day of illness.
Methods : A retrospective chart review was conducted of all children with Kawasaki disease who were admitted to Ewha Mokdong Hospital between January... |
-
-
- Usefulness of Low Risk Criteria for Serious Bacterial Infection
Among Febrile Infants Younger than Three Months of Age
-
So Hyun Kim, Ji Ah Jung, Hae-Soon Kim, Eun Sun Yoo, Sejung Sohn, Jeong Wan Seo, Seung Joo Lee
-
Clin Exp Pediatr. 2002;45(8):967-972. Published online August 15, 2002
-
|
Purpose : A retrospective study was undertaken to evaluate the usefulness of low risk criteria for identifying febrile infants younger than three months unlikely to have serious bacterial infection.
Methods : We conducted a retrospective study of 527 infants younger than three month with a axillary temperature ≥37.4℃. If they met the following all four criteria, appear well, WBC 5,000- 20,000/mm3,... |
-
-
- Clinical Features of Atypical Kawasaki Disease
-
Mi Young Heo, Su Jung Choi, Hae Soon Kim, Sejung Sohn
-
Clin Exp Pediatr. 2002;45(3):376-382. Published online March 15, 2002
-
|
Purpose : To identify clinical and laboratory features of atypical Kawasaki disease(KD), and to develop criteria for early diagnosis of atypical KD patients.
Methods : All patients with KD treated at our hospital from January 1998 to June 2000 were reviewed retrospectively.
Results : Among a total of 167 patients, 28(16.8%) were atypical KD of which seven(25%) were infants. Among the... |
-
-
- Effects of Umbilical Arterial Catheterization on
Intestinal Hemodynamics
-
Sejung Sohn, Su Jung Choi, Jung An Yang, Eun Ae Park
-
Clin Exp Pediatr. 2000;43(5):650-657. Published online May 15, 2000
-
|
Purpose : An umbilical arterial catheter(UAC) in the high position reduces the lumen of the aorta and may thereby impair blood supply to the intestine. Effects of UAC on intestinal blood flow were investigated.
Methods : With the measurement of the aortic diameter, pulsed Doppler ultrasonography was performed in 23 fasting newborns to measure blood flow velocities(peak systolic velocity, end-diastolic velocity,... |
-
-
- Percutaneous Closure of Patent Ductus Arteriosus Using Coil Embolization
-
Mi Jung Kang, Sejung Sohn, Eun Jung Bae, In Seng Park, Seong Ho Kim
-
Clin Exp Pediatr. 1998;41(3):369-377. Published online March 15, 1998
-
|
Purpose : Percutaneous closure with occluding coils has been recently described as a method of nonsurgical treatment of the small patent ductus arteriosus(PDA). The snare-assisted technique or detachable coil has been newly developed, improving coil delivery and eliminating the incidence of coil embolization. This method is also applicable to residual PDA following surgical ligation or device implantation. The study purpose... |
-
-
- The Effects of Lipo Prostaglandin E1(EglandinⓇ) in Patients with Ductus Dependent Congenital Heart Disease
-
Sejung Sohn, Seong Ho Kim, Eun Jung Bae, In Seung Park
-
Clin Exp Pediatr. 1996;39(8):1111-1121. Published online August 15, 1996
-
|
Purpose : The adverse reactions of prostaglandin E1(PGE1) are troublesome in the preoperative
management of critical patients with ductus dependent congenital heart disease, and a preparation
with less adverse reactions is preferable. The effects of Lipo PGE1, a new preparation of PGE1
contained in lipid microspheres, were compared with those of conventional PGE1(PGE1-CD).
Methods : Lipo PGE1 was infused at a rate of 5... |
-
-
- The Effects of Adriamycin on Ionic Currents in Single Cardiac Myocytes of the Rabbit
-
Sejung Sohn
-
Clin Exp Pediatr. 1995;38(8):1093-1106. Published online August 15, 1995
-
|
Purpose : The study objective was to elucidate the possible pathophysiologic mechanism of Ca overload by adriamycin (ADR) which is associated with ADR- induced cardiotoxicity.
Methods : The effects of ADR on ionic currents were studied using the whole cell voltage clamp technique in single cardiac myocytes of the rabbit.
Results : The magnitude of the inward tail current, recorded at -70mV... |
-
-
- Periventricular Leukomalacia
-Ultrasonographic Findings, Risk Factors and Neurological Outcome-
-
Kyeong Hee Cho, Myoung Jae Chey, Sejung Sohn, Kil Hyun Kim, Hak Soo Lee, Young Seok Lee, Dae Joong Kim
-
Clin Exp Pediatr. 1993;36(5):693-704. Published online May 15, 1993
-
|
The thirty eight newborn infants with periventricular leukomalacia who were admitted to the neonatal intensive care unit of Gil General Hospital from March 1, 1988 to June 30, 1991, were investigated for ultrasonographic findings, risk factors and neurological outcome.
The results were as follows:
1) There were 38 cases of PVL including 21 echogenic flarings and 17 cystic PVL뭩.
2) Mean birth weight... |
-
-
- A Case of Acute Megakaryoblastic Leukemia in infantwith down Syndrome.
-
Jang Sik Moon, Hae Young Hwang, Sejung Sohn, Hak Soo Lee, Heum Rye Park
-
Clin Exp Pediatr. 1990;33(10):1441-1446. Published online October 31, 1990
-
|
Acute megakaryoblastic leukemia is an uncommonly recognized disorder that is characterized by
rapidly progressive proliferation of atypical megakaryocytes and their precursor cells, and fatal
course.
Abnormalities in chromosome 21 may have more than relationship to it.
The authors report a case of acute megakaryoblastic leukemia in a 17 day-old male patient who
was admitted for evaluation of high fever and dyspnea.
The infiltration of atypical megakaryocytes... |
-
-
- A Case of Ulcerative Colitis.
-
Yang Mi Jung, Jong Sik Moon, Sejung Sohn, Hak Soo Lee
-
Clin Exp Pediatr. 1989;32(8):1144-1149. Published online August 31, 1989
-
|
Ulcerative colitis is a chronic inflammatory bowel disease of unknown etiology affecting the
mucosa of colon and rectum.
We have recently experienced a case of ulcerative colitis in a 13 year-old girl.
The diagnosis was established by clinical feature, barium enema, colonoscopy and rectal biopsy. |
-
-
- Percutaneous Transluminal Angioplasty in Four Children with Takayasu's Arteritis.
-
Byung Kiu Park, Sejung Sohn, Chung Il Noh, Young Soo Yun, Chang Yee Hong, Kyung Mo Yeon, In One Kim
-
Clin Exp Pediatr. 1987;30(4):441-449. Published online April 30, 1987
-
|
Percutaneous transluminal angioplasty (PT A) was done in four children with Takayasu’s arteritis
at Seoul National University Children’s Hospital in 1986. Successful results were obtained in all cases.
But one child with narrowing of the innominate artery, thoracic aorta and occlusion of the left
subclavian artery showed the most dramatic improvement clinically as well as radiologically because
the lesions were focal. PT A is... |
-
-
- Clinical Study on the Hypoplastic Right Heart Syndrome.
-
Sejung Sohn, Soon Ung Kang, Chung Il Noh, Jung Yun Choi, Yong Soo Yun, Chang Yee Hong, Dug Ha Kim, Jong Lin Rhi
-
Clin Exp Pediatr. 1987;30(3):281-290. Published online March 31, 1987
-
|
A clinical observation was made on 12 cases of the hypoplastic right heart syndrome who were
admitted to the department of Pediatrics, Seoul National University Hospital from January 1978 to
May 1986. The -results were as follows;
1) The ratio of female to male was 1:1 and, according to the anatomic classification by Khoury, 6
cases were in type 1, 4 cases in type II... |
-
-
- Clinical Observation of Truncus Arteriosus.
-
Sang Kyu Park, Young Soo Kim, Sejung Sohn, Chung Il Noh, Jung Yun Choi, Yong Soo Yun, Chang Yee Hong
-
Clin Exp Pediatr. 1987;30(1):45-54. Published online January 31, 1987
-
|
This is the report on 10 cases of truncus arteriosus, experienced at the Seoul National University
Hospital, during past 7 years from Jan. 1979 to Dec. 1985. The results of observations were as follows;
1) There were 6 males and 4 females, and according to Collett and Edwards’ classification, 5 cases
were in type 1, 4 case were in type II and 1 case... |
-
-
- Cardiac Malposition.
-
Sejung Sohn, Jung Yun Choi, Yong Soo Yun, Chang Yee Hong, Je G Chi
-
Clin Exp Pediatr. 1986;29(2):186-202. Published online February 28, 1986
-
|
Cardiac malposition refers to any position of the heart other than a left-sided heart in a situs solitus individual.
Authors analyzed the clinical, radiological, operative and autopsy findings of 69 patients with cardiac malpositions by segmental approach to describe the internal cardiac anatomy and their arterial connections.
1) Male to female sex ratio was 1.23 : 1 and 68% of cases were under... |
-
-
|